Abstract: The time characteristics of suspected nosocomial infection outbreak and nosocomial infection aggregation in a neurological specialized hospital in recent five years are retrospectively analyzed to find out the early identification factors of nosocomial infection outbreak,continuously optimize the management of nosocomial infection through the refined management of daily infection control work,and explore the early warning,timely intervention,and comprehensive control mechanisms for nosocomial infection outbreaks in neurological specialized hospitals,so as to provide basis for improving the management of nosocomial infection. Contact transmission mainly causes the outbreak of suspected nosocomial infection in the neurological specialized hospital. Strengthening the pre-examination and triage system,establishing and perfecting the three-level management system of hospital infection control and supervision,training and regular meeting have a positive impact on the prevention and control of nosocomial infection outbreak. A neurological specialized hospital should focus on preventing the outbreak of nosocomial infection caused by contact transmission. Strengthening the refined management of nosocomial infection control can effectively reduce the outbreak of nosocomial infection.

Key words: neurology, nosocomial infection outbreak, early warning, early intervention